granulose

In situ hybridization results showed that the positive signals for Frizzled 2 were highly detected in the oocyte and stroma in proestrus stage, while moderate or weak Frizzled 2 mRNAs were localized in the oocyte, granulose cells, stroma and corpus luteum from estrus to diestrus.

原位杂交结果表明：动情前期卵母细胞和基质中Frizzled2信号强；而后三个时期的卵母细胞、颗粒细胞、基质和黄体中具有中等或微弱信号。

Results In different degree, different dosages of tonifying kidney formula can improve follicular growth, increase VEGF, promote vascular formation, enhance Bcl-2 expression and decrease granulose cell Caspase-3 content and distribution.

结果补肾复方大小剂量组均可不同程度促进卵泡生长，增加VEGF，促进卵巢血管生成，增强Bcl-2表达，降低颗粒细胞Caspase-3含量及分布。

In vitro, after pre-culture for 12 h, the proliferation of granulose cells from small yellow follicles was remarkably enhanced in a dose-dependent manner after treatment with ghrelin ( 1-1000 ng/ ml).

鸡小黄卵泡的颗粒细胞在体外预培养12h后，用1-1000ng/ml的Ghrelin处理24h，细胞增殖效应呈现出剂量依赖性。