immunodeficient

Methods From Apr.1999 to May 2002, in the First Affiliated Hospital of Zhengzhou University, an experimental colitis model was established in which chronic colitis was induced by transfer of syngeneic CD45RB, CD~+_4T cells into severe combined immunodeficient ( SCID) mice.

方法1999-04~2002-05比利时鲁汶大学医学院和郑州大学第一附属医院使用严重联合免疫缺陷型（SCID）小鼠，并体内移植入同基因源性CD45RB CD4+T细胞诱发慢性结肠炎发生。

The origin and breeding of the immunodeficient animal& T 、 B 、 NK cell deficient mouse ( BNX mouse) was reviewed and the biological characteristics and applications in haematology 、 oncology 、 immunology and other fields were given in details.

本文综述了T、B和NK细胞联合免疫缺陷BNX小鼠的培育，详细介绍其一般的生物学特性及其在血液学、肿瘤学、免疫学和微生物学等方面的应用。

A Breeding of T and NK Cell Combined Immunodeficient PBI/ 2 Beige Nude Mouse and Its Primary Application in the Biological Research on Cancer

T和NK细胞联合免疫功能缺陷型&PBI/2beige裸鼠的培育及其在癌生物学研究中的初步应用