核酸

Along with the continuously go deep into of the research of biosensors based on functional nucleic acid, detection techniques have been developed quickly for small organic molecules, inorganic ions, peptides, proteins, organelles and other non-nucleic acid molecules.

随着对以功能核酸为敏感元件的生物传感器不断深入研究，基于功能核酸分子对有机小分子、无机离子、多肽、蛋白质、细胞器等非核酸分子的检测技术得到了很快的发展。

The nucleic acid detection systems ( nucleic acid real-time fluorescent RT-PCR detection system, nucleic acid RT-PCR detection system, OIE standard nested RT-PCR detection method) were more sensitive than antigen-captured ELISA detection system. The detection limit gap was 2 orders of magnitude at least.

在灵敏度方面，3种核酸检测体系（核酸实时荧光RT-PCR检测体系、核酸RT-PCR检测体系、OIE标准巢式RT-PCR检测方法）均优于抗原捕获ELISA检测体系，检出限间的差距均在2个数量级以上。

Artificial nuclease can mimic the function of natural nuclease by breaking the backbone of DNA site-specifically. And these small molecules can also be used as molecular biology tools and gene therapy agents.

人工核酸切割分子，又称人工核酸酶，是用化学方法合成的一类能模拟天然核酸酶断裂核酸骨架的功能小分子。它可以发展成为有用的分子生物学工具和基因治疗药物。