thalassanemia

To investigate the morphological features of mediastinal extramedullary hematopoietic tissue in β-thalassanemia patients and its diagnosis, the morphological features of tumor-like hyperplastic in extramedullary hematopoietic tissue were analyzed by using fine needle aspiration cytological ( FNAC) biopsy and compared with bone marrow smear sample.

为了研究β地中海贫血伴髓外造血组织瘤样增生细胞形态特点其及诊断，对纵隔髓外造血组织瘤样增生用细针抽吸活组织行细胞学检测（FNAC），并与骨髓片进行比较分析。

The percentage of ones who received prenatal diagnosis improve 37% after the thalassanemia intervention, and 1 case among every 2.7 cases receiving prenatal diagnosis was achieved because of the intervention. 4 babies with severe thalassanemia were avoided.

干预后促进的产前诊断比干预前提高了37%，每2.7例产前诊断就有1例是由于预措施促成，并避免了4例重型地贫儿的出生。

Methods β-thalassanemia carriers were screened by using routine examination and the red cell osmotic fragility analysis. Hb electrophoresis and reverse dot blot hybridization were used to diagnose and analyze gene types.

方法通过血液常规检查和红细胞渗透脆性分析筛查地贫患儿，用血红蛋白电泳和基因诊断明确诊断并分析基因型。