sialyl

The positive expression of sialyl Lewis X was observed in 85 of 90 patients with colorectal carcinoma ( 94.4%). The cellular membrane and cytoplasma of cancer tubules and the mucous pool of the mucinous adenocarcinoma were strongly stained.

大肠癌组织中唾液酸化Lewis x阳性表达率为94.4%（85/90），主要分布于癌组织腺管细胞膜、细胞浆以及粘液腺癌的粘液湖内。

It was found that sialyl residue was not essential for the cell adhesion to Fn, but was important in the cell adhesion to Ln and chemotactic cell invasion, and very crucial in the cell adhesion to HUVEC and chemotactic migration.

结果表明：表面糖链末端SA对细胞黏附至Fn并不必需，对细胞黏附至Ln和细胞的趋化性侵袭却至为重要，而对细胞黏附至HUVEC以及趋化性迁移则为关键性残基。

Objective To explore the clinical significance of the expression of sialyl Lewis-X ( sLex) antigen in the patients with primary colorectal cancer or colorectal liver metastases.

目的探讨唾液酸化的路易斯寡糖-X（sLex）抗原在大肠癌及大肠癌肝转移病人中表达的临床意义。