pyrazinamide

In part 2, a new hyperuricemia model that is more similar to patient is established by oxonic acid and pyrazinamide.

本部分研究利用尿酸酶抑制剂氧嗪酸和抑制肾脏排泄尿酸的药物吡嗪酰胺，建立一种与人类高尿酸血症天津医科大学博士研究生学位论文更为接近的高尿酸血症动物模型。

Method: Anti-TB bone was made of reconstituted bone xenograft ( RBX) combined with 4 antituberculosis drugs ( Isoniazide, Rifampicin, Pyrazinamide, Ethambutol) at certain concentration and encapsulated by gelatin and polycaprolactone.

方法：采用明胶和聚己内酯复合包裹法将异烟肼、利福平、吡嗪酰胺和乙胺丁醇等4种抗结核药物按一定浓度和配比与重组合异种骨（RBX）复合，制备抗结核骨。

Pyrazinamide ( PZA) is an important component in short-course tuberculosis chemotherapy.

吡嗪酰胺（PZA）是结核病短程化疗中的一线抗结核药物，由吡嗪酰胺酶转换成为活性形式吡嗪酸而生效。