frizzled

In situ hybridization results showed that the positive signals for Frizzled 2 were highly detected in the oocyte and stroma in proestrus stage, while moderate or weak Frizzled 2 mRNAs were localized in the oocyte, granulose cells, stroma and corpus luteum from estrus to diestrus.

原位杂交结果表明：动情前期卵母细胞和基质中Frizzled2信号强；而后三个时期的卵母细胞、颗粒细胞、基质和黄体中具有中等或微弱信号。

To this end, we investigated the expression pattern of Frizzled 2 in the mouse ovary during estrous cycle by real-time Q-PCR, in situ hybridization, Western blotting and immunohistochemistry.

本研究通过实时定量PCR、原位杂交、Western印迹杂交和免疫组织化学等方法，检测了Frizzled2在动情周期的小鼠卵巢中的表达情况。

In this study, We found that during estrous cycle, Frizzled 2 mRNA and protein exhibited the highest level in the proestrus stage and rapidly decreased from estrus to diestrus.

研究发现，动情前期的Frizzled2mRNA和蛋白水平最高，自动情期到间情期快速减弱。