dihydropyrimidine

Objective To probe the relationship between the chemosensitivity of 7 gastrointestinal cancer cell lines and the expression levels of metabolic enzymes of fluoropyrimidines including thymidylate synthase ( TS), thymidine phosphorylase ( TP), and dihydropyrimidine dehydrogenase ( DPD).

目的探讨氟尿嘧啶类药物代谢酶&胸苷酸合成酶（TS）、胸苷磷酸化酶（TP）和二氢嘧啶脱氢酶（DPD）表达水平与人胃肠道肿瘤细胞化疗敏感性的关系。

Aim: To investigate the difference between the mRNA levels of thymidine phosphorylase ( TP), thymidylate synthase ( TS), and dihydropyrimidine dehydrogenase ( DPD) between Chinese and North European breast cancer patients.

胸苷酸合成酶、胸腺嘧啶脱氧核苷磷酸化酶及二氟嘧啶脱氢酶的表达与乳腺癌预后的相关性目的：检测北欧和中国人乳癌患者TP、TS、DPD mRNA水平的差异。

Objective To investigate the relationships among the expression of thymidylate synthase ( TS), thymidine phosphorylase ( TP), and dihydropyrimidine dehydrogenase ( DPD) and the prognosis of breast cancer.

目的通过检测乳腺癌标本中胸苷酸合成酶（TS）、胸腺嘧啶脱氧核苷磷酸化酶（TP）、二氟嘧啶脱氢酶（DPD）表达情况，探讨乳腺癌的生物学行为与上述3个指标之间的相关性。