deoxycytidine的翻译

Methods To investigate the changes of DNA methyltransferase 1 ( DNMT_1) mRNA and methylation status of progesterone receptor double promotors ( PRA, PRB) before and after 5-Aza-2 ′-deoxycytidine treatment.

方法用5-杂氮-2′-脱氧胞苷处理白血病细胞株HL-60、K562和Jukat，分析处理前后DNA甲基转移酶1mRNA表达和孕酮受体双启动子（PRA、PRB）甲基化状态的变化。

BACKGROUND& OBJECTIVE: 5-Aza-2 ′-deoxycytidine ( 5-Aza-CdR) is an inhibitor of DNA methyltransferase; it may reactivate methylated antioncogene, therefore, inhibit the growth of cancer cells.

背景与目的：5-杂氮-2′-脱氧胞苷是DNA甲基转移酶抑制剂，能使因甲基化而失活的抑癌基因重新激活，进而抑制肿瘤的生长。

Objective To investigate the expression of deoxycytidine kinase ( DCK) and cytidine deaminase ( CDA) gene in children with acute leukemia and to explore the relationship between gene expression and clinical response to cytarabine ( Ara-C).

目的通过测定急性白血病（AL）患儿脱氧胞苷激酶（DCK）和胞苷脱氨酶（CDA）基因的表达，探讨其与阿糖胞苷（Ara-C）耐药及临床疗效间的关系。