BPDE的音标

Objective The carcinogenesis mechanism of benzo [ α] pyrene dihydrodiol epoxide ( BPDE) is still unclear according to the known genes interaction with BPDE. So it is an urgent problem to screen more BPDE target susceptible genes.

研究目的：目前已知的与二羟环氧苯并芘（BPDE）相互作用的基因尚不能阐明BPDE的致癌分子机制，寻找出更多的BPDE致癌易感基因是个亟需解决的问题。

BPDE-DNA adducts in white blood cell could be used as effect biomarker of DNA damage in population by PM2.5 without special exposure to PAHs.

若无特殊PAHs暴露，可将外周血白细胞BPDE-DNA加合物作为PM2.5致人群DNA损伤的效应生物标志。

The changes of 8-OH-dG in the progress of carcinogenesis were detected in human bronchial epithelial cells induced by Benzo ( a) pyrene diol-epoxide ( BPDE) and sulfide nickel ( NiS) in vitro.

并利用苯并（a）芘代谢产物B（a）P二醇环氧化物（BPDE）和结晶型硫化镍（NiS）诱导的体外人支气管上皮细胞转化癌变模型，检测癌变进程中8OH dG的变化。