ALA-PDT

Photodynamic therapy on serum testosterone and estradiol levels. Compared with the control group, ALA-PDT and red light irradiation alone has not change the serum testosterone and estradiol levels, there are no significantly different ( P 0.05). 3.

光动力治疗对血清睾酮，雌二醇水平的影响与空白对照组比较，ALA.PDT和单纯红光照射均未引起血清睾酮，雌二醇水平的显著差异（PO05）。

Also, we investigated the role of cell apoptosis, cell cycle and mitochondria membrane potential changes, subcellular localization of ALA-Pp ⅸ, and some molecular changes to understand the mechanism of ALA-PDT for esophageal cancer. Objectives: 1.

通过研究ALA-PDT对食管癌细胞凋亡、细胞周期及线粒体膜电位的影响、ALA的亚细胞定位以及一些相关基因及蛋白的变化以探讨其主要作用机制。

The expression of Bcl-2, Bcl-xL and FADD genes were all significant down regulation at 24 h after ALA-PDT on the Eca-109 cell, while Bax was significant up-regulation ( all P0.05).

Bcl-2、Bcl-xL、FADD在ALA-PDT作用于Eca-109细胞24h后其表达均均显著下调，而Bax基因的表达则显著上调，与对照组相比，其差异均有统计学意义（P均0.05）。